2022

Wednesday, February 2, 2022
1:00pm – 2:00pm

mathew fountain

Matthew Fountain, Ph.D.

Research Associate, MacKeigan Lab
Obstetrics, Gynecology & Reproductive Biology
Michigan State University

Presented via Zoom https://msu.zoom.us/j/97602236100

Meeting ID: 976 0223 6100
Passcode: OBGYN

Wednesday, March 2, 2022
1:00pm – 2:00pm

Manoj Madhavan

Manoj Madhavan

Graduate Student, Arora Lab
Institute for Quantitative Health Science and Engineering
Obstetrics, Gynecology & Reproductive Biology
Michigan State University

Presented via Zoom https://msu.zoom.us/j/97602236100

Meeting ID: 976 0223 6100
Passcode: OBGYN

Wednesday, March 30, 2022
1:00pm – 2:00pm

jeong

Jae Wook Jeong, Ph.D.

Professor
Obstetrics, Gynecology & Reproductive Biology
Michigan State University

Presented via Zoom
https://msu.zoom.us/j/97602236100

Meeting ID: 976 0223 6100
Passcode: OBGYN

Wednesday, April 6, 2022
1:00pm – 2:00pm

Valerie Flores MD

Valerie Flores, MD

Assistant Professor
Division of Reproductive Endocrinology and Infertility
Obstetrics, Gynecology and Reproductive Sciences
Yale School of Medicine

Grand Rapids Research Center, Rm. 1102

Optional Zoom: https://msu.zoom.us/j/97602236100

Meeting ID: 976 0223 6100
Passcode: OBGYN

 

Illuminating the (uterine) path: from embryo movement to implantation

riplo aroha thumb

Ripla Arora, PhD Assistant Professor
Obstetrics and Gynecology
Michigan State University

Wednesday, September 28, 2022
11:00 AM ET in IQ Atrium
OR Join via Zoom
957 5713 3265
PASSWORD: BME/IQ

Although much is known about the molecular signaling during implantation, the uterine 3D architecture that facilitates embryo development remains unknown. Imaging the mouse embryo and the uterine milieu simultaneously we uncovered patterns of embryo movement and dynamic shape changes in the uterine lumen and glands in preparation for implantation. When applied to mouse mutants with known implantation defects, this method detected striking peri-implantation abnormalities in uterine morphology that cannot be visualized by histology. Analyzing the uterine and embryo structure in 3D for genetic mutants, hormonal perturbations and pregnancies treated with pathway inhibitors is helping us uncover novel molecular pathways and global structural changes that contribute to successful implantation of an embryo. Our studies have implications for understanding how structure-based embryo-uterine communication is key to determining an optimal implantation site, which is necessary for the success of a pregnancy

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