OBGYN Researcher Jaewook Jeong awarded a Mary Kay Foundation Grant of $100,000 for the study of endometrial cancer.
Endometrial cancer is the most common gynecologic malignancy, with an estimated 63,230 new cases in 2018. Although early-stage and low grade endometrial cancer generally exhibits a favorable prognosis, recurrent endometrial cancer is incurable with currently available standard therapies for most women. We have developed a preclinical model for metastatic and recurrent endometrial cancer that implicates coexistent Pten and Mig-6 mutations in endometrial cancer. The project will investigate tumor suppressor roles of MIG-6 in metastasis and recurrence of endometrial cancer.