College of Human Medicine researchers have received a National Institutes of Health grant to study the connection between a gene important for normal cell survival and endometriosis, a painful disease which affects one in 10 women of reproductive age. The disease also has a significant economic impact, estimated at $95 billion annually in the U.S. in lost wages and medical expenses.
The gene called NOTCH1 is “needed for normal reproduction, but when it goes awry it has a significant role in endometriosis,” said Asgi Fazleabas, PhD, a University Distinguished Professor of Obstetrics, Gynecology and Reproductive Biology.
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