Michigan State Unversity

  • Wednesday, May 12, 2021
    7:00am – 8:00am

    Ryan Marquardt

    Gregory Gressel, MD

    Director of Gynecologic Cancer Clinical Research
    Spectrum Health Medical Group
    Clinical Associate Professor, Department of Obstetrics and Gynecology
    Michigan State University

    Presented via Zoom
    https://msuhipaa.zoom.us/j/99638177698
    Meeting ID: 996 3817 7698
    Passcode: 220234

  • Genna Moldovan,
    Graduate Assistant
    Fazleabas Lab

    Department of Obstetrics, Gynecology & Reproductive Biology Michigan State University

    Wednesday, October 28, 2019
    1:00 pm – 2:00 pm

    Presented via Zoom
    By Room: Dial—162.255.36.156 One tap mobile
    Meeting ID: 976 0223 6100 +13017158592,,97602236100#
    Passcode: OBGYN +13126266799,,97602236100#

    Join with a personal device: https://msu.zoom.us/j/97602236100

    Moldovan RIP FLyer

  • OBGYN abstract title "ARID1A Loss Results in Non‐Receptive Endometrium with FOXA2 Deficiency in Endometriosis‐Related Infertility" by Ryan M. Marquadt has been selected for the SRI President’s Plenary Award. This award will be presented at our 66th Annual Scientific Meeting, which will be held in Paris, France, March 12 – 16, 2019.

    The President’s Plenary Awards recognize the four highest ranked abstracts chosen for presentation at the President’s New Investigator Plenary Session. The Society has always sought a means by which to encourage young investigators to present their research at our meeting. The award encourages many young investigators to submit high‐quality abstracts.

  • (Updated April 15th 2024)

    Title/DescriptionSponsorPIAmountStart DateEnd Date
    Reproductive and Developmental Sciences Program T32 Training Grant NIH Keith Latham, PhD
    Asgi Fazleabas, PhD    		 $1,485,595 6/1/16 4/30/27
    Reproductive and Developmental Sciences Program T32 Training Grant NIH Keith Latham, PhD
    Asgi Fazleabas, PhD    		 $1,485,595 6/1/16 4/30/27
    Women's Outcomes Research and Knowledge (WORK) AbbVie Stacey Missmer, ScD $2,956,535 4/1/18 12/31/24
    What is Endometriosis (WisE)? Deep phenotyping to advance diagnosis and treatment NIH Stacey Missmer, ScD 3,868,014 9/1/18 5/31/25
    Strong Beginnings (Healthy Start Initiative – Eliminating Racial/Ethnic Disparities) HRSA - Spectrum Health System LeeAnne Roman, PhD $472,085 4/1/19 4/30/24
    Infertility History and Chronic Disease Profile NIH Stacey Missmer, ScD $3,276,321 5/15/19 4/30/25
    In Vitro Fertilization Outcomes After Cancer NIH Barbara Luke, ScD $370,550 8/5/19 7/31/24
    Innate Immune Mechanisms at the Maternal-Fetal Interface in Normal and Superovulatory Pregnancy NIH - Rutgers University Ripla Arora, PhD $54,509 8/21/19 7/31/24
    Patient-specific targeting of uterine fibroids NIH - NICHD Jose Teixeira, PhD $2,441,496 8/28/19 4/30/25
    Alliance for Innovation on Maternal Health Community Care Initiative (AIM CCI) HRSA - Spectrum Health System Cristian Meghea, PhD $106,920 4/1/20 9/30/24
    Myometrial stem cells NIH Jose Teixeira, PhD $430,375 6/1/20 5/31/24
    A Smartphone Intervention for Pregnancy Smoking Cessation with Peer Support NIH Cristian Meghea, PhD $751,923 8/6/20 8/31/24
    Single-molecule Analysis of the DNA Damage Response in Living Cells NIH Jens Schmidt, PhD $2,137,302 9/30/20 5/31/25
    State Opioid Relief for Use Disorders MDHHS Cara Poland, MD $3,909,839 10/1/20 9/30/24
    Regulation of Endometriotic Lesion Development by NOTCH1 NIH Asgerally Fazleabas, PhD $2,757,437 4/1/21 2/28/26
    Meeting women where they are: Multilevel intervention addressing racial disparities in maternal morbidity and mortality - Administrative Supplement NIH Jennifer Johnson, PhD & Cristian Meghea, PhD $219,090 5/1/21 4/30/25
    Menstrual health during the Covid-19 pandemic: A longitudinal study among young people with and without endometriosis NIH Stacey Missmer, ScD $274,576 5/1/21 4/30/25
    Covid-19 Vaccination and Menstrual Health NIH Stacey Missmer, ScD $200,003 5/1/21 4/30/25
    Epigenetic regulatory mechanisms and therapeutic opportunities in endometriosis NIH Ronald Chandler, PhD $1,682,375 8/15/21 6/30/26
    Defining the role of TCAB1 and its phase separation in telomerase assembly NIH Jens Schmidt, PhD $919,740 9/1/21 7/31/25
    Hospital Engagement Addiction Resources Team (HEART) Michigan Health Endowment Fund Board of Directors Cara Poland, MD $500,000 12/1/21 5/31/24
    Marriott Fund for Clinical Innovation in Endometriosis J. Willard and Alice S. Marriott Foundation Stacey Missmer, ScD $91,331 1/1/22 12/31/25
    Regulation of Endometriotic Lesion Development by E-proteins Society of Endometriosis and Uterine Disorders Yong Song, PhD $23,528 1/1/22 12/31/24
    S-Flt siRNA Therapy for Pre-eclampsia Comanche BioPharma Asgerally Fazleabas, PhD $367,068 3/1/22 8/31/24
    Endometriosis, Pelvic Pain, and Covid-19 Immunologic Response Boston Center for Endometriosis Stacey Missmer, ScD $300,959 8/1/22 7/31/24
    Increasing Minority Physician and APRN Clinician-scientist Research Training To Equalize Addiction Medicine (IMPACT TEAM) NIH Cara Poland, MD $1,337,280 8/15/22 6/30/27
    A Smartphone Intervention for Pregnancy Smoking Cessation with Peer Support NIH Cristian Meghea, PhD $567,744 9/1/22 8/31/25
    Signaling Mechanisms that Modulate Uterine 3D Structure for Pregnancy Success NIH Ripla Arora, PhD $1,984,108 9/1/22 5/31/27
    Molecular mechanisms of endometrial progesterone resistance Univ of Missouri - NIH Ripla Arora, PhD $146,071 9/1/22 4/30/25
    The role of cholesterol biosynthesis in metastatic and recurrent endometrial cancer Univ of Missouri - NIH Ripla Arora, PhD $204,209 9/23/22 1/31/27
    Addressing Disparities in Maternal Mortality and Severe Morbidity for Medicaid-insured Pregnant/Postpartum Individuals of Color: A Multilevel, Community-Clinical Intervention for Hypertension Disorder Michigan Health Endowment Fund   Lee Anne Roman, PhD $367,190 1/1/23 12/31/24
    Developing a clinically-relevant genetically engineered mouse model for Nut
    carcinoma    		 NIH - NCI Bin Gu, PhD $2,145,235 1/5/23 12/31/27
    Novel biomarkers and pathways of persistent endometriosis-associated pain across the life course Univ of Michigan - NIH Stacey Missmer, ScD $213,846 3/23/23 2/29/28
    Strong Beginnings Program – Familias Fuertes y Saludables Corewell Health Lee Anne Roman, PhD $55,000 4/1/24 3/31/25
    A baboon model for uterine fibroids Oregon Health & Science University Jose Teixeira, PhD $46,000 5/1/23 10/31/24
    Transcriptomic Analysis of Uterine Fibroids for Drug Discovery Society for Reproductive Investigation Emmanuel Paul, PhD $20,000 7/1/23 12/31/24
    Role of Cellular Senescence in Development of Endometriosis Society for Reproductive Investigation Yong Song, PhD $20,000 7/1/23 6/30/24
    Maternal Health Multilevel Intervention/s for Racial Equity (MIRACLE) Center NIH - NICHD Cristian Meghea, PhD
    Jennifer Johnson, PhD    		 $18,494,512 8/17/23 7/31/30
    All of Us Research Program Trans-America Consortium of the HCSRN NIH Christine, Johnson, PhD
    Henry Ford Health    		 $18,393,034 9/1/23 8/31/24
    Pilot for Treatment of Post-partum Women MDHHS Cara Poland, MD $24,128 10/1/23 9/30/24
    State Opioid Response (MI-CARES) MDHHS Cara Poland, MD $1,087,575 10/1/23 9/30/24
    Strong Beginnings: Reaching Black and Hispanic Women at Greatest Risk to Improve Outcomes MDHHS Lee Anne Roman, PhD $699,786 10/1/23 9/30/24
    Providing Technical Assistance To Michigan Communities for the State’s Opioid Settlement Funds Michigan Public Health Institute Cara Poland, MD $200,000 10/1/23 9/30/24
    A Longitudinal Study of the Epidemiology of Endometriosis Department of Defense Madhavi Kulkarni, PhD $312,998 8/15/24 8/14/26

  • Adjunct Faculty

    Oana Blaga, PhD

    Adjunct Faculty

    Joshi Niraj, PhD

    Adjunct Faculty

    Mili Thakur, MD

    Adjunct Faculty

  •  spartan place saver

    Biography

    Dr. Loree received her PhD in clinical psychology from Wayne State University. She is a licensed clinical psychologist in the State of Michigan, and holds certification in perinatal mental health (PMH-C). Dr. Loree completed her doctoral internship at Yale University School of Medicine, and a two-year postdoctoral fellowship through the VA’s Interprofessional Advanced Fellowship in Addiction Treatment at VA Connecticut Healthcare System and Yale University School of Medicine. She joined the Center for Health Policy & Health Services Research at Henry Ford Health as an Assistant Scientist in 2017, and has been an Assistant Professor in the Departments of Obstetrics, Gynecology & Reproductive Biology and Pediatrics & Human Development at Michigan State University College of Human Medicine since 2022.

    Research Interests

    Dr. Loree’s research broadly focuses on mental health and substance use disorders, particularly during the perinatal period, and involves efforts to develop, refine, and implement evidence-based practices. She is also interested in technology-based interventions and complementary and integrative health approaches (e.g., mindfulness, yoga). Currently, she is Principal Investigator/Co-Principal Investigator on a CDC-funded project implementing technology-based screening, brief intervention and referral to treatment (SBIRT) for alcohol use among reproductive age women; the Perinatal Behavioral Health Integration program (funded by the Ethel & James Flinn Foundation); Healthy You, Healthy Pregnancy, Healthy Baby (H3; funded by the Michigan Health Endowment Fund); and the MAMA project (funded by a PCORI Engagement Award). She is also a Co-Investigator on several federally-funded studies focused on implementing evidence-based interventions and health services research in perinatal mental health, suicide prevention, and substance use disorders.

    Publications

  • The Center for Research In Reproduction and Women’s Health Inaugural Symposium was held Friday 10/14 in Detroit, MI and was a great success by many measures. We convened in person to learn of the diverse research topics that spanned the continuum of women’s health. We saw our unique strength of discovery across the boundaries of molecular, cell, epidemiology, public health sciences and clinical services to investigate pressing women’s health challenges. We learned the early benefits our internal funding of pilot projects that have already resulted in NIH grant submissions.

  • MSU College of Human Medicine

    Affiliated Obstetrics/Gynecology Residency Network (AOGRN)

    Monique Swain, MD

    Monique Swain, MD

    Henry Ford Hospital, Obstetrics and Gynecology Residency Program  

    Program Director
    Detroit, Michigan

    Read More
    Omari Young, MD

    Omari Young, MD

    Hurley MSU/CHM Obstetrics & Gynecology Residency Program

    Program Director
    Flint, Michigan

    Read More
    Raisa Platte, MD

    Raisa Platte, MD

    Spectrum Health MSU/CHM Obstetrics and Gynecology Residency Program

    Program Director
    Grand Rapids, MI

    Read More
    Abigail M. Ramseyer

    Abigail M. Ramseyer

    Sparrow OBGyn

    Co-Program Director
    Lansing, Mi

    Read More
    Kristina VanderMark, MD

    Kristina VanderMark, MD

    Ascension Providence Hospital MSU/CHM Obsterics & Gynecology Residency Program

    Program Director
    Southfield, MI

    Read More

    Simulated Resources

  • Congratulations to Jessyca Judge, MD candidate 2023, who is this year’s recipient of the Bruce Drukker Endowed Award of Excellence in Obstetrics and Gynecology.

  • In this year’s Manatt Health and the AMA report, “The Fight to End the Nation’s Overdose Epidemic and Restore Compassionate Care: Profiles in Leadership,” highlights the work of more than 25 practicing physicians, policymakers, dedicated researchers and advocates who illustrate how the strategies across these six domains can be turned into reality.

    Cara Poland, MD Board-certified Addiction Medicine Physician Cara Poland, MD, MEd, FACP, DFASAM, of Michigan State University's Department of Obstetrics, Gynecology and Reproductive Biology contributed with her article Training future addiction medicine leaders.

    The Fight to End the Nation’s Overdose Epidemic and Restore Compassionate Care: Profiles in Leadership

  • Professional Photo

    Cara Poland, MD, M.Ed, FACP, DFASAM was trained in internal medicine at St. Joseph Mercy Hospital in Ann Arbor, Michigan and in addiction medicine at Boston Medical Center in Boston, Massachusetts. She has an interest in educating physicians and physicians-in-training to improve care for patients with substance use disorders and alcohol use disorders. Her clinical focus is working with pregnant and parenting women and their families.

  • Christine Cole Johnson

    Research Interests:

    Dr. Christine Cole Johnson is an epidemiologist with a long-time research focus on birth cohort studies and the environmental epidemiology and etiology of allergic disorders, with the goal of the primary prevention of allergic disorders and asthma. She has also had a sustained interest in health disparities, focused on racial/ethnic/SES differences in health and disease.

    Dr. Johnson has spent most of her professional years working as a scientist embedded within a vertically integrated health care system, Henry Ford Health (HFH), which serves an extraordinarily large and diverse population. She served as a co-investigator on the Inner-City Asthma Consortium from 2009-2021. She is the original epidemiologist on the Childhood Allergy Study (CAS) birth cohort beginning in 1987 and continuing, and the PI of the Wayne County Health, Environment, Allergy, and Asthma Longitudinal Study (WHEALS) birth cohort established from 2003-2007 and still ongoing. She is the site PI for both these cohorts and the MAAP and CANOE birth cohorts as part of the CREW consortium, a group of birth cohorts collaborating together as part of the national NIH Environmental influences on Childhood Health Outcomes (ECHO) research program and Dr. Johnson is a co-investigator on the Michigan State University ECHO consortium, serving as the asthma epidemiologist. Her current P01 renewal (MAAP2), focused on the importance of the maternal and infant microbiome in immune development, is based on birth cohort research. She also has experience in patient-centered research as PI of an AHRQ funded Patient Centered Outcomes Research Center that developed resources to successfully enhance the development and management of research projects which contributed to her success in obtaining one of the NIH Precision Medicine Cohort “All of Us” health care provider contracts. She was the lead epidemiologist at the HFH site for the PLCO and NLST cancer screening trials and has been an active member of the Health Care Systems Research Network (HCSRN).

    Bibliography:

    Dr. Johnson obtained a masters degree in public health in epidemiology from the University of Michigan and a PhD in epidemiology from the University of Texas School of Public Health in Houston TX. She is the Chair of Public Health Sciences at HFH and a professor in the Department of Obstetrics, Gynecology and Reproductive Biology in the College of Human Medicine at Michigan State University. She has been the Deputy Director of the Wayne State University (WSU) CURES NIEHS-funded Environmental Health Sciences Center since 2016, serving as the primary liaison between HFH and WSU in a collaborative effort to foster significant, relevant and actionable environmental health research programs.

    Awards and Honors:

    • Lilienfeld Student Prize Paper Award, Society for Epidemiologic Research (1986)
    • Fellow, American Academy of Allergy, Asthma and Immunology (2005-present)
    • Henry Ford Distinguished Scientist Award (2012)
    • Invited Member, American Epidemiological Society (8/2014-)
    • FP Global Thinker Award (2016)
    • Crain’s Detroit Business Most Notable Women in Health Care (2020)
    • HFHS 2021 Outstanding Publication of the Year
    • Member, Sigma Xi Scientific Research Honor Society (2022-)

    NCBI Publications (300+)

  • The State of Michigan received an $800 million settlement from some of the national opioid litigation. As part of this, the legislature created an Opioid Advisory Commission. The Commission will guide the appropriate appropriation of these dollars through recommendations to the legislature. Dr. Cara Poland was appointed to this Commission by the Senate Majority Leader’s office and elected by her peers on the Commission to be the inaugural Chairperson for the Committee for three years. Congratulations, Dr. Poland, on this recognition.

  • David Kambach

    Research interest

    Dr. Kalmbach is a licensed clinical psychologist. He earned his PhD in clinical psychology from Kent State University after completing his internship at the Ann Arbor Veterans Health System – University of Michigan Medical School consortium in 2014. He then completed an APA-accredited postdoctoral residency at the University of Michigan Medical School where he received clinical and research training in perinatal mental health and behavioral sleep medicine. He was funded by the National Heart, Lung, & Blood Institute on a T32 fellowship from 2016 to 2018 for his work in sleep disorders research. He joined Henry Ford Health in 2018 and currently serves as the Co-Director of the Perinatal Sleep Health Institute and the Director of its clinical core, the Perinatal Sleep Clinic. He is currently funded by the National Institute of Mental Health (NIMH) for his research on treating insomnia and depression during pregnancy. He recently completed an NIMH study on preventing depression in the general adult population through the use of sleep therapeutics in primary care. He has previously been funded by the American Academy of Sleep Medicine for his research on sleep in pregnancy. Presently, Dr. Kalmbach is Associate Professor of Obstetrics, Gynecology, and Reproductive Biology at Michigan State University College of Human Medicine and Assistant Scientist in the Division of Sleep Medicine at Henry Ford Health.

    Bibliography

    Reflecting his clinical practice and research over the past decade, Dr. Kalmbach primarily focuses on sleep and mental illness during pregnancy and postpartum. His work has shown that half of pregnant women suffer from clinical insomnia and that untreated insomnia increases risk for depression and suicidal thoughts during pregnancy and postpartum. Dr. Kalmbach is especially interested in cognitive arousal at night (e.g., worry or ruminating while trying to sleep) as a risk factor insomnia, depression, and suicidal thoughts during peripartum. His recent work has shown that reducing nocturnal cognitive arousal is an important treatment mechanism for improving sleep and mood through psychotherapy.

    Dr. Kalmbach developed Perinatal Understanding of Mindful Awareness for Sleep (PUMAS), which is a psychotherapy protocol designed specifically for pregnant women with insomnia. PUMAS combines behavioral sleep strategies and mindfulness with all components tailored to pregnancy. The PUMAS manual is freely available upon request or from The Henry Ford Perinatal sleep Health Institute. Published reports show PUMAS improves sleep, alleviates depression, and reduces nighttime worry and rumination during pregnancy.

    Dr. Kalmbach also has interests outside of peripartum and has published several important works in the general adult population, including evidence showing insomnia is a robust risk factor for major depression; treating insomnia prevents development of major depression; treating insomnia alleviates and prevents suicidal thoughts; mindfulness-based therapy is efficacious for treatment-resistant insomnia; and poor and insufficient sleep increases depression, anxiety, and medical errors among physicians.

  • Excerpts from our conversation with Dr. Stacey Missmer, an NIH-funded women’s health specialist at Michigan State University.

    NIHNiH: How common are painful periods in teens?

    Missmer: Moderate to severe pain during one’s period—that is, pain that impacts someone's life—is reported by about 35 to 40% of teen and adult women in the U.S. It isn't in any way rare.

  • Sascha Drewlo, Ph.D., has been awarded the 2020 Jean P. Schultz Biomedical Research Endowment fund.  

    Dr. Drewlo is an associate professor in the Department of Obstetrics, Gynecology and Reproductive Biology at the Michigan State University College of Human Medicine. His research is focused on closing the gap between the diagnosis of placental dysfunction and its treatment to provide every pregnancy the best possible outcome. Drewlo seeks to develop novel approaches for fetal genetic analysis as well as overall pregnancy status during the first trimester of pregnancy from a simple pap smear. 

    Read Full Article

  • Join Michigan State University’s outstanding and unique women’s health research program focused on national and international priorities across the life course and discovery in the areas of basic science, clinical and population science, implementation, and translational science at the interface of gynecology and reproductive biology. Be one of a group of diverse new faculty, working in collaboration with MSU’s renowned scholars in a range of scientific, engineering, biomedical, and public health disciplines in an inclusive culture that supports interdisciplinary research and scholarship.

  • Wegienka Ganesa

    BIOGRAPHY

    Dr. Ganesa Wegienka, the Director of Women's Health Research at Henry Ford Health in the Public Health Sciences Department, is leading research that focuses on improving women's health. One area of her research is dedicated to understanding and addressing uterine fibroids, which are non-cancerous tumors in the uterus. These fibroids are the leading cause for women undergoing hysterectomy, a surgery to remove the uterus. They can cause heavy periods, anemia, pelvic pain, and discomfort, impacting women's quality of life.

    What makes Dr. Wegienka's work even more crucial is the significant impact uterine fibroids have on different racial groups. African American women are more likely to develop fibroids at an earlier age and have larger fibroids compared to white women. This racial disparity has been a pressing issue that needs to be addressed. To tackle this problem, she is leading a study called the Study of Environment, Lifestyle and Fibroids (SELF). This study, funded by the National Institutes of Health (NIH), is one of the most important fibroid studies to date. The study is based in Detroit and exclusively focuses on Black and African American individuals. By following these participants over time and regularly screening for fibroids, this study provides valuable insights into the natural history of fibroids and potential causes.

    She also leads other vital Women's Health research studies funded by the NIH. One of these studies, known as ePRESTO, is a collaboration with Boston University. It aims to explore how environmental toxins and lifestyle factors can impact fertility and pregnancy in women. Another significant study, the inVitD Trial, is conducted at Henry Ford Health in Detroit and the Research Triangle Park area in North Carolina. This study focuses on investigating the relationship between vitamin D levels and menstrual cycles.

    Dr. Wegienka and the dedicated Women's Health Research teams at Henry Ford Health are committed to understanding the experiences of women who undergo hysterectomy. While many studies focus solely on clinical factors like hospital stay or blood loss, Dr. Wegienka’s work emphasizes what matters to patients. The work delves into understanding how women perceive and comprehend their surgeries, considering the physical and emotional implications. The work also explores the impact of post-surgery regret and the financial stress that may be associated with treatment.

  • 965 Wilson Road, A631B

  • Stacey Missmer is a professor of obstetrics, gynecology and reproductive biology in the Michigan State University College of Human Medicine. Her current research study, Women’s Outcomes Research and Knowledge, or WORK, is focused on diagnosing and treating pelvic pain in women and girls.

    Missmer will be presenting her research, Reproductive Health Science: Multidisciplinary Discovery and Community Engagement, at the Board of Trustees meeting on June 18.

    Read Full Article

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