Jennifer E. Johnson has been awarded a five-year, $3,358,550 grant to study treatment for major depressive disorder among women who have recently experienced perinatal loss—miscarriage, stillbirth, or early neonatal death. This study is the first fully powered randomized trial of treatment for any psychiatric disorder following perinatal loss.
September 14, 2020
The rates of major depressive disorder (MDD) among women who have recently experienced perinatal loss—miscarriage, stillbirth, early neonatal death—are three times that of the general population of women. Mood difficulties can persist up to four years after the loss, suicide rates are high, and PTSD rates are seven times that of mothers of living infants. MDD causes significant impairment, yet treatment has been inadequate.
For more than 70 years, the Endocrine Society has recognized the meritorious achievements of endocrine researchers and clinicians worldwide. These awards recognize endocrinologists for seminal research, meritorious service, leadership and mentorship, innovation, international contributions, public service, translation of science to practice, and lifetime achievement.
Award categories honor the achievements of endocrinologists at all stages of their careers, recognizing those at the pinnacle of the field as well as young endocrinologists who are making a mark. The dedication, commitment, and achievements of current and past award recipients have each earned a place in endocrine history.
MSU’s new provost, Teresa Woodruff, has recently been named a recipient of one of the Endocrine Society’s 2021 Laureate Awards — top honors that recognize the highest achievements in the endocrinology field.
Endocrinologists specialize in hormone-related diseases and dedicate their research and clinical care to people with conditions like diabetes, thyroid disorders, obesity, hormone-related cancers, growth problems, osteoporosis and infertility.
Dr. Jae Wook Jeong, PhD has received a new National Institute of Health, R01 grant in the amount of $2.65 million for a five year period. The project entitled, “Molecular Mechanisms of Endometrial Progesterone Resistance” will focus on diseases of the female reproductive tract which represent a significant problem in women’s health. To solve these problems, they will try to understand the mechanisms of uterine receptivity and implantation to develop better treatments that may be currently out of reach. Endometrial progesterone resistance implies a decreased responsiveness of target tissue to bioavailable progesterone, and such an impaired progesterone response is seen in the endometrium of women with non-receptive endometrium. However, relatively little is known about the molecular mechanisms and the precise etiology and hormone regulation of endometrial progesterone resistance in female infertility. This NIH R01 project will utilize new genetic model systems to discover and understand these critical mechanisms.
Please welcome Dr. Teresa Woodruff, PhD, Foundation Professor, to the Department of Obstetrics Gynecology and Reproductive Biology. Dr. Woodruff is an internationally recognized expert in ovarian biology and, in 2006, coined the term “oncofertility” to describe the merging of two fields: oncology and fertility. Woodruff holds more than 10 U.S. Patents and was elected to the National Academy of Inventors (2017). She has been active in education not only at the professional level but also with high school students. To this end, she founded the Oncofertility Saturday Academy (OSA), one of several high school outreach programs that engages girls in basic and medical sciences. For this work, she was awarded the Presidential Award for Excellence in Science Mentoring in an Oval Office ceremony by President Obama (2011).
Please welcome Dr. Bin Gu to the Obstetrics, Gynecology and Reproductive Biology and Institute for Quantitative Health Science and Engineering. Dr. Bin Gu received his Ph.D. in Cell Biology from the College of Life Sciences at Zhejiang University in China in 2013. There he discovered the expression and function of the Autoimmune Regulator (Aire) gene in embryonic stem (ES) cells. In 2013, he moved to Toronto for his postdoctoral training in Dr. Janet Rossant’s Lab in SickKids Hospital. During his postdoctoral training, he continued to study the function of Aire in early mouse embryos and revealed a novel function of Aire in mitotic spindle assembly in ES cells and early embryos, and provided a plausible explanation for the fertility defect in AIRE mutant APECED patients and Aire knockout mice. Recently, Dr. Gu has developed 2C-HR-CRISPR, a transformative technology for complex genome editing in mice.
Please welcome Dr. Steven Ondersma, PhD, to the department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine. Dr. Ondersma joins us from the Departments of Psychiatry & Behavioral Neurosciences and Obstetrics & Gynecology at Wayne State University. His primary interest is in computer-delivered assessment and motivational interventions for substance use and other risk factors among pregnant and postpartum women. He is a Fellow of the American Psychological Association (Division 37), former Editor of the journal Child Maltreatment, and a member of the Motivational Interviewing Network of Trainers. He has served as an invited presenter for numerous NIH topical meetings as well as for the White House Office of National Drug Control Policy and the Institute of Medicine. He has been PI on multiple NIH/CDC research grants focusing on the development and validation of novel screening techniques and technology-based brief interventions.
Today, March of Dimes announces three young investigators as recipients of the 2020 Basil O’Connor Starter Scholar Research Awards: Dr. Ripla Arora from Michigan State University, Dr. Corina Lesseur from Icahn School of Medicine at Mount Sinai and Dr. Jamie Lo from Oregon Health & Science University. The annual award supports early-career scientists embarking on independent research careers who are committed to fighting for the health of all moms and babies.
Named for the first March of Dimes chairman and president, the award carries a $150,000 grant and is part of the nonprofit’s effort to promote actionable science that turns observations from the laboratory into interventions that support healthy moms and strong babies.