We are interested in studying reproductive tract and gonadal developmental with major research interests focused on four complementary studies directly related to women's health and reproduction. These include (1) dissecting the signaling mechanisms common to Wnt/ß-catenin and PI3K in the gonads and uterus and the pathophysiological consequences when they are dysregulated, which we believe might be an underlying cause of uterine fibroid development and gonadal and endometrial cancers; (2) identification and molecular characterization of the uterine stem/progenitor cells and the functional effects of endocrine disruption on their behavior during uterine development and during normal uterine functions; (3) cryopreservation and maturation of primary follicles in vitro for somatic cell nuclear transfer applications and as a mechanism to rescue the fertility of patients who are having their ovaries removed or destroyed by gonadotoxic therapies; (4) The fourth research interest is to investigate the therapeutic use of MIS in ovarian cancer and as an inhibitor of ovarian follicle development.
Research Technologist I
George, Jitu, Ph.D.
Dr. Jitu George received his MS from Bangalore University, India and his PhD from the Department of Molecular and Integrative Physiology at University of Kansas Medical Center. His current research focus is to investigate the molecular mechanisms involved in uterine fibroid development and progression and identify suitable targets for therapeutic intervention.
Mukherjee, Ananda, PhD
Dr. Ananda Mukherjee received his MS from North Bengal University, India and his Ph.D. from Jadavpur University, India. Ananda did his postdoctoral training at University of Rhode Island, USA and have joined MSU as a Research Associate. His current research focus is to explore the role of stromal tumor suppressors in the high grade epithelial cancers.
Patterson, Amanda, Ph.D.
Dr. Amanda Patterson received her MS from the Department of Animal Sciences at Colorado State University and her PhD from the Department of Animal Sciences at Washington State University. Her current research focus includes the identification, characterization and regulation of uterine stem/progenitor cells, and the etiology of uterine fibroids.
Sharma, Plavita, BS
Research Technologist I
Plavita Sharma earned her Bachelor’s in Biotechnology and Genetic Engineering from India, and her MS in Cellular and Molecular biology from Grand Valley State University. Her research focus includes molecular pathways and interactions in human disease.